Health

Lack of Sleep Disrupts the Brain and Increases Appetite

Chronic sleep deprivation may be behind unintended weight gain


Recent scientific studies show that lack of sleep doesn’t just affect focus and mood, but also has a direct impact on appetite regulation and may significantly contribute to the risk of obesity. Consistently getting fewer than six hours of sleep per night disrupts brain function, affects hunger hormones, and alters how we perceive food.

A disorganized brain and impaired decision-making

When sleep-deprived, the prefrontal cortex—responsible for decision-making, self-control, and logical thinking—functions less efficiently. Meanwhile, brain regions tied to reward and pleasure, such as the striatum, become more active, especially in response to high-fat, high-sugar, and calorie-dense foods.

In simple terms, a tired brain struggles to resist temptation, and unhealthy foods appear more appealing. This neurological imbalance encourages impulsive eating behaviors, such as late-night snacking or overeating.

Hormonal imbalance: leptin and ghrelin at play

Sleep deprivation also alters the balance of two key hormones that regulate hunger:

  • Leptin, produced by fat cells, signals fullness to the brain. When we sleep too little, leptin levels drop, prolonging hunger.

  • Ghrelin, produced in the stomach, triggers appetite. Its levels tend to rise when we’re sleep-deprived, encouraging excessive food intake.

This hormonal shift creates a significant increase in appetite, even though the body’s actual energy requirements haven’t changed.

Long-term effects that shouldn’t be ignored

Multiple studies have found that people who regularly sleep less than six hours per night are at a higher risk of becoming overweight or obese compared to those who sleep seven to eight hours. This correlation is even stronger among children and teenagers.

Beyond weight gain, chronic lack of sleep is also associated with increased risks of type 2 diabetes, high blood pressure, cardiovascular disease, and mental health issues, including depression and anxiety.

An underestimated public health issue

In today’s fast-paced world, where people often sacrifice sleep for work or screen time, it’s more important than ever to recognize the vital role of sleep in maintaining mental, physical, and metabolic health.

Getting enough sleep—ideally between 7 to 9 hours per night—is essential not just for daily performance, but also for maintaining a healthy weight and a balanced relationship with food.

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