Study reveals the secret of the inefficacy of some alzheimer’s treatments
A research team has discovered the existence of 5 types of Alzheimer‘s disease, revealing the secret behind the ineffectiveness of several therapeutic drugs.
Dutch scientists reached this conclusion after examining proteins found in the cerebrospinal fluid in the spinal cord and brain of over 400 Alzheimer‘s patients.
The scientists identified 5 different subtypes of Alzheimer‘s disease, each with clinical effects on treatment.
Among the types discovered by the scientists is one that leads to the overgrowth of brain cells, resulting in the production of abnormal proteins, ultimately leading to Alzheimer‘s.
The scientists pointed out that those affected by this type tend to have the longest average lifespan compared to patients with other types, surviving 9 years after the disease diagnosis.
The scientists concluded that the second type involves problems with the brain’s internal immune system, while the third type is associated with issues in protein production in the brain.
As for the fourth type, it is linked to problems with blood supply to the brain, and the fifth type is associated with issues in the blood-brain barrier, which in turn prevents the passage of certain sensitive substances to the brain.
In conclusion of their study, the scientists advised a reevaluation of previous clinical trials testing Alzheimer‘s treatments to determine their effectiveness for each type.
